Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922578 | 0.78 | CES2 (0.34) | CES2CES1ESR1ESR2PDPK1 | |
| SCHEMBL9570698 | 0.78 | ESR1 (0.46) | ESR1ESR2CTSL | |
| SCHEMBL9570629 | 0.77 | KDM1A (0.40) | PDE2AFAAH | |
| SCHEMBL9560934 | 0.76 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL9570685 | 0.76 | ACP3 (0.41) | — | |
| SCHEMBL9570752 | 0.76 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL9570592 | 0.76 | SLC6A2 (0.42) | ESR1ESR2AKR1C3AKR1C2 | |
| SCHEMBL9570758 | 0.76 | HDAC4 (0.42) | CES2CES1 | |
| SCHEMBL30255116 | 0.74 | CES2 (0.47) | CES2CES1PDPK1ADRB1ADRA2A | |
| SCHEMBL308893 | 0.74 | CES2 (0.47) | CES2CES1ESR1ESR2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0240978-A2 | Ether compounds, process for their preparation, compositions containing the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |