Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570842 | 0.84 | ADRB2 (0.40) | — | |
| SCHEMBL9560934 | 0.79 | ESR1 (0.44) | LMNASMN1; SMN2ESR1ESR2CYP3A4 | |
| SCHEMBL9570577 | 0.78 | RORC (0.43) | ALDH1A1LMNASMN1; SMN2CYP2D6 | |
| SCHEMBL9570685 | 0.78 | ACP3 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL9570786 | 0.76 | CES2 (0.40) | ESR1ESR2AKR1C3AKR1C2 | |
| SCHEMBL27940674 | 0.75 | AHR (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1LMNA | |
| SCHEMBL9874617 | 0.75 | AHR (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1LMNA | |
| SCHEMBL9570823 | 0.75 | ESR1 (0.44) | ALDH1A1HTTSMN1; SMN2ESR1ESR2 | |
| SCHEMBL9570752 | 0.74 | ESR1 (0.37) | ALDH1A1LMNASMN1; SMN2ESR1ESR2 | |
| SCHEMBL22397193 | 0.72 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0240978-A2 | Ether compounds, process for their preparation, compositions containing the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |