SCHEMBL9570752

SCHEMBL9570752

Cc1ccc(C(CO)C(F)(F)F)cc1C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
ALDH1A1 P00352 2/20 0.35
S1PR1 P21453 1/20 0.34
TRPA1 O75762 1/20 0.33
PTGS1 P23219 1/20 0.33
CACNA1C Q13936 1/20 0.33
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570735 0.79 ESR1 (0.44) ESR1ESR2ALDH1A1
SCHEMBL9570847 0.76 ACP3 (0.40)
SCHEMBL9570786 0.76 CES2 (0.40) ESR1ESR2
SCHEMBL9570823 0.75 ESR1 (0.44) ESR1ESR2ALDH1A1POLBSMN1; SMN2
SCHEMBL9570592 0.74 SLC6A2 (0.42) ESR1ESR2ALDH1A1LMNASMN1; SMN2
SCHEMBL6002859 0.74 TRPA1 (0.39) ALDH1A1TRPA1PTGS1CACNA1CTP53
SCHEMBL15071422 0.74 ALDH1A1 (0.36) ESR1ESR2ALDH1A1TRPA1PTGS1
SCHEMBL13703416 0.74 ESR1 (0.48) ESR1ESR2ALDH1A1TRPA1PTGS1
SCHEMBL9570831 0.74 PPARG (0.57) ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL23983161 0.72 LMNA (0.39) ESR1ESR2ALDH1A1S1PR1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed