SCHEMBL9570836

SCHEMBL9570836

C=CCc1ccc(C(C=O)C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP3A4 P08684 2/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
XDH P47989 1/20 0.34
PPARG P37231 2/20 0.33
PPARD Q03181 2/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH2 P05091 1/20 0.33
GAA P10253 1/20 0.33
GABRA1 P14867 1/20 0.33
AKR1B1 P15121 1/20 0.33
HPGD P15428 1/20 0.33
CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570843 0.79 TSHR (0.41) ALDH1A1SMN1; SMN2TP53TSHRMAPT
SCHEMBL9570579 0.77 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL9570671 0.76 THRB (0.38) ALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL9570650 0.76 CA12 (0.44) ALDH1A1SMN1; SMN2TP53MAPTMEN1
SCHEMBL9570876 0.74 IDO1 (0.35) ALDH1A1SMN1; SMN2GAAESR1ESR2
SCHEMBL10455686 0.73 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL9570785 0.72 ESR1 (0.46) ALDH1A1SMN1; SMN2CYP3A4TP53ALOX15
SCHEMBL9570796 0.72 TYR (0.48) ALDH1A1KDM4EGAACYP2D6MAPK1
SCHEMBL9570777 0.72 TSHR (0.40) TP53ALOX15TSHRPPARGGAA
SCHEMBL9570654 0.72 CYP2A6 (0.38) ALDH1A1MAPTMEN1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed