SCHEMBL9570876

SCHEMBL9570876

O=CC(c1ccc(F)cc1)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.35
TDO2 P48775 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
ALPG P10696 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABBR2 O75899 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570639 0.81 HTR2A (0.35) ESR1ESR2CTSL
SCHEMBL9570745 0.81 CES2 (0.43) ALDH1A1CES2CES1
SCHEMBL9570654 0.81 CYP2A6 (0.38) ESR1ESR2ALDH1A1GAA
SCHEMBL9570796 0.81 TYR (0.48) ALDH1A1LMNAGAA
SCHEMBL9570777 0.81 TSHR (0.40) IDO1TDO2HDAC4HDAC7HDAC5
SCHEMBL1225030 0.80 CYP2D6 (0.39) LMNA
SCHEMBL9570579 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL9570684 0.78 TSHR (0.44) HDAC1ALDH1A1LMNA
SCHEMBL9570822 0.78 CES2 (0.40) CES2CES1
SCHEMBL9570588 0.78 PDE2A (0.32) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed