SCHEMBL9570936

SCHEMBL9570936

Fc1ccc(COCC(c2ccc3c(c2)OCO3)C(F)(F)F)cc1Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 6/20 0.37
EDNRA P25101 1/20 0.37
MAOB P27338 2/20 0.37
TP53 P04637 2/20 0.36
GPR55 Q9Y2T6 2/20 0.36
HTR1A P08908 1/20 0.36
CNR1 P21554 1/20 0.36
HTR7 P34969 1/20 0.36
HTR6 P50406 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 2/20 0.36
BLM P54132 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560453 0.86 MAOB (0.42) LMNAHTTMAPTKMT2AEDNRA
SCHEMBL9570782 0.86 GRM5 (0.33) MAOB
SCHEMBL9570666 0.86 TACR1 (0.35) MAOB
SCHEMBL9628951 0.85 MAOA (0.39) LMNAHTTMAPTKMT2AMAOB
SCHEMBL9560935 0.84 LTA4H (0.36)
SCHEMBL9561512 0.83 TACR1 (0.36) HTTALDH1A1TDP1L3MBTL1GAA
SCHEMBL9570878 0.82 MAPK14 (0.34)
SCHEMBL9570874 0.82 TACR1 (0.39) SMN1; SMN2ALDH1A1
SCHEMBL9570739 0.82 FFAR1 (0.34)
SCHEMBL9570626 0.82 HIF1A (0.34) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed