SCHEMBL9570626

SCHEMBL9570626

CC1(C)Cc2cc(C(COCc3ccc(F)c(Oc4ccccc4)c3)C(F)(F)F)ccc2O1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.34
EPAS1 Q99814 2/20 0.34
DAGLA Q9Y4D2 3/20 0.33
DUT P33316 1/20 0.32
ABHD6 Q9BV23 1/20 0.31
MAOB P27338 3/20 0.31
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570782 0.83 GRM5 (0.33) MAOBFFAR1
SCHEMBL9570889 0.83 FABP5 (0.33) DUTFFAR1
SCHEMBL9570936 0.82 LMNA (0.39) MAOB
SCHEMBL9570878 0.82 MAPK14 (0.34) DUTFFAR1
SCHEMBL9570666 0.81 TACR1 (0.35) DUTMAOBFFAR1
SCHEMBL9560456 0.81 MAPK14 (0.35) DUTFFAR1
SCHEMBL9570739 0.80 FFAR1 (0.34) DUTFFAR1
SCHEMBL9570693 0.79 TACR1 (0.36) DUTFFAR1
SCHEMBL9570632 0.79 DUT (0.35) DUTFFAR1
SCHEMBL9561249 0.79 FFAR1 (0.40) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed