Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 8/20 | 0.39 |
| ▸ | HTR2C | P28335 | 8/20 | 0.39 |
| ▸ | HTR2B | P41595 | 8/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629106 | 0.86 | FDFT1 (0.35) | HTR2AHTR2CHTR2BHTR1AHTR7 | |
| SCHEMBL9804347 | 0.86 | MAOB (0.45) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL9570936 | 0.85 | LMNA (0.39) | MAOBHTR1AHTR7TP53GPR55 | |
| SCHEMBL10649374 | 0.84 | MAOA (0.39) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL10652424 | 0.84 | MAOA (0.39) | MAOAMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL9493734 | 0.82 | CETP (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7929110 | 0.82 | FDFT1 (0.37) | — | |
| SCHEMBL7934903 | 0.81 | TTR (0.41) | — | |
| SCHEMBL7922569 | 0.80 | FDFT1 (0.40) | TP53 | |
| SCHEMBL407786 | 0.80 | LTA4H (0.41) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233834-B1 | INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-22 | — | — | EP | claimed |