Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572006 | 0.86 | PTPRC (0.50) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9561901 | 0.81 | CCR6 (0.56) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28629974 | 0.77 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28616027 | 0.77 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9561922 | 0.76 | CCR6 (0.51) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9572023 | 0.75 | MEN1 (0.51) | HSD17B10KDM4EALDH1A1HPGDCCR6 | |
| SCHEMBL9572001 | 0.75 | PTPRC (0.50) | HSD17B10KDM4EALDH1A1HPGDCCR6 | |
| SCHEMBL9572011 | 0.74 | CCR6 (0.40) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9562597 | 0.74 | PTPRC (0.59) | GAACCR6HKDC1 | |
| SCHEMBL9572015 | 0.74 | RAB9A (0.43) | HSD17B10KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |