Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562391 | 0.81 | NTRK1 (0.54) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL9572029 | 0.80 | NPC1 (0.40) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL9572003 | 0.74 | HSD17B10 (0.47) | RAB9ANPC1GAAALDH1A1MAPT | |
| SCHEMBL27734112 | 0.73 | PTPN1 (0.55) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL9572006 | 0.72 | PTPRC (0.50) | GAAALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL571017 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL572045 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL571607 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL572109 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1MITFGAAL3MBTL1 | |
| SCHEMBL15695046 | 0.71 | ALDH1A1 (0.58) | RAB9ANPC1MITFGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |