Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26130465 | 0.84 | ALOX5 (0.40) | ALDH1A1TSHR | |
| SCHEMBL7407277 | 0.84 | REN (0.36) | RENCCR6PAX8ALDH1A1KCNH2 | |
| SCHEMBL1573556 | 0.80 | TSHR (0.40) | PPIBPPIDPPIGALDH1A1L3MBTL1 | |
| SCHEMBL12762248 | 0.80 | CETP (0.43) | ALDH1A1KCNH2L3MBTL1TSHR | |
| SCHEMBL6949217 | 0.79 | TAAR1 (0.42) | TSHR | |
| SCHEMBL8960248 | 0.79 | TSHR (0.41) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL6951407 | 0.78 | HTT (0.44) | HTTADRA1ACCR6PAX8ALDH1A1 | |
| SCHEMBL10473639 | 0.78 | CARM1 (0.41) | ALDH1A1PRMT6TSHR | |
| SCHEMBL1415899 | 0.78 | TSHR (0.38) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL8495462 | 0.78 | CCR6 (0.38) | CCR6PAX8ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525973-A2 | Substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |