SCHEMBL95734

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31520485	0.91	MEN1 (1.00)	MEN1KMT2ACA12CA1CA2
	SCHEMBL27749455	0.82	NAMPT (0.64)	MEN1KMT2AKDM4EPOLBTSHR
	SCHEMBL6893687	0.82	ALDH1A1 (0.79)	MEN1KMT2AALDH1A1NPC1SMN1; SMN2
	SCHEMBL5315377	0.80	LTA4H (0.76)	MEN1KMT2ACA12CA1CA2
	SCHEMBL8585760	0.78	NPC1 (0.67)	MEN1KMT2AALDH1A1NPC1SMN1; SMN2
	SCHEMBL14192211	0.77	ALDH1A1 (0.72)	MEN1KMT2AALDH1A1NPC1SMN1; SMN2
	SCHEMBL5312292	0.77	LMNA (0.67)	MEN1KMT2ACA12CA1CA2
	SCHEMBL3839081	0.76	MEN1 (0.74)	MEN1KMT2AALDH1A1NPC1SMN1; SMN2
	SCHEMBL5312685	0.76	LTA4H (0.76)	MEN1KMT2ACA12CA1CA2
	Hydrochloric Acid SCHEMBL10681906	0.76	KMT2A (0.64)	MEN1KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.