Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574173 | 0.81 | MAOB (0.43) | MAOBAPPMEN1KMT2ABCHE | |
| SCHEMBL456296 | 0.79 | FOLH1 (0.43) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10076826 | 0.79 | MAOB (0.43) | MAOBAPPMEN1KMT2A | |
| SCHEMBL10592068 | 0.77 | MAOB (0.40) | MAOBAPPPPARGMEN1KMT2A | |
| SCHEMBL10477760 | 0.76 | MEN1 (0.47) | MAOBMEN1KMT2ABCHEACHE | |
| SCHEMBL10077369 | 0.75 | CDK1 (0.42) | MAOBMEN1KMT2ABCHEACHE | |
| SCHEMBL10477860 | 0.75 | KDM4E (0.41) | MAOBMEN1KMT2ABCHEACHE | |
| SCHEMBL9863679 | 0.73 | LMNA (0.45) | BCL2L1MCL1MEN1KMT2A | |
| SCHEMBL10077370 | 0.72 | MAOB (0.35) | MAOBPPARGPPARABCHEACHE | |
| SCHEMBL10462952 | 0.71 | MAOB (0.41) | MAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126375-A | Asthma, chronic bronchitis | GLAXO GROUP LTD. (GB) | 1992-06-30 | — | — | US | disclosed |