Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574909 | 0.88 | HTT (0.44) | KMT2AMEN1ALDH1A1PABPC1HTT | |
| SCHEMBL9574732 | 0.87 | SMN1; SMN2 (0.45) | KMT2AMEN1ALDH1A1PKMPABPC1 | |
| SCHEMBL9574724 | 0.87 | PGR (0.50) | KMT2AMEN1ALDH1A1PKMKDM4E | |
| SCHEMBL9574660 | 0.84 | SMN1; SMN2 (0.42) | KMT2AMEN1ALDH1A1PKMPABPC1 | |
| SCHEMBL8868652 | 0.84 | PKM (0.50) | KMT2AMEN1ALDH1A1PKMNPC1 | |
| SCHEMBL9413326 | 0.82 | POLB (0.56) | KMT2AMEN1ALDH1A1PABPC1NPC1 | |
| SCHEMBL7874555 | 0.79 | MAPT (0.51) | KMT2AMEN1ALDH1A1NPC1HTT | |
| SCHEMBL9574751 | 0.79 | MEN1 (0.51) | KMT2AMEN1ALDH1A1PABPC1POLB | |
| SCHEMBL9574755 | 0.79 | KCNK3 (0.42) | KMT2AMEN1ALDH1A1PABPC1KDM4E | |
| SCHEMBL9574705 | 0.77 | CACNA1B (0.46) | KMT2AMEN1ALDH1A1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |