Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574790 | 0.88 | KMT2A (0.49) | HTTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL9574751 | 0.82 | MEN1 (0.51) | MEN1KMT2APOLBPABPC1AR | |
| SCHEMBL8868644 | 0.81 | HTT (0.53) | HTTMEN1KMT2APOLBMAPT | |
| SCHEMBL9574745 | 0.81 | SMN1; SMN2 (0.39) | HTTMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL9574758 | 0.81 | NR3C1 (0.49) | HTTMEN1KMT2APOLBMAPT | |
| SCHEMBL9413326 | 0.80 | POLB (0.56) | HTTMEN1KMT2APOLBMAPT | |
| SCHEMBL9574694 | 0.78 | MEN1 (0.47) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7870592 | 0.77 | MAPT (0.50) | HTTMEN1KMT2AMAPTCA1 | |
| SCHEMBL7869433 | 0.77 | MAPT (0.50) | HTTMEN1KMT2AMAPTCA1 | |
| SCHEMBL9574772 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AMAPTPABPC1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |