Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL14879867 | 0.95 | NPSR1 (0.31) | NPSR1L3MBTL1MAPT | |
| SCHEMBL14278445 | 0.74 | NPSR1 (0.34) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL9754962 | 0.73 | MAPT (0.36) | MAPTALDH1A1HTTNOS3NOS1 | |
| SCHEMBL4428965 | 0.71 | — | — | |
| SCHEMBL12630691 | 0.70 | — | — | |
| SCHEMBL2690654 | 0.69 | — | — | |
| SCHEMBL10588951 | 0.67 | MAPT (0.42) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL2692984 | 0.65 | KDM4E (0.31) | L3MBTL1 | |
| SCHEMBL15021 | 0.65 | RAB9A (0.31) | — | |
| SCHEMBL1392715 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161168-A1 | AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161167-A1 | NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | WO | disclosed |
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| EP-2768307-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3094626-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| EP-3094626-B1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| CN-107074800-B | substituted bicyclic heteroaryl compounds as RXR agonists | 康内克斯生命科学私人有限公司 | 2019-11-12 | — | — | CN | disclosed |
| EP-2935291-B1 | IRIDIUM COMPLEXES USED IN OLIGOMERS, POLYMERS OR DENDRIMERS IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| EP-3100723-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-2785178-B1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20110003784-A1 | Opsin-binding ligands, compositions and methods of use | BIKAM PHARMACEUTICALS INC. | 2011-01-06 | — | — | US | disclosed |
| WO-2010147653-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
| US-4931458-A | Heterocyclic rodenticidal compounds, compositions containing the compounds, and methods of use | HOFFMANN-LA ROCHE INC. (US) | 1990-06-05 | — | — | US | disclosed |
| US-4816476-A | BENZO(B)THIENYL GROUP OR BENZOFURAN SUBSTITUTED GROUPS | HOFFMANN-LA ROCHE INC. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0098591-B1 | HETEROCYCLIC COMPOUNDS AND RODENTICIDES CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-07-08 | — | — | EP | disclosed |
| US-4659735-A | Benzofuranyl (thienyl) propenyl derivatives useful as rodenticides | HOFFMANN-LA ROCHE INC. (US) | 1987-04-21 | — | — | US | disclosed |
| US-4617146-A | TOBACCO; FOODS; BEVERAGES; PERFUMES | GIVAUDAN CORPORATION (US) | 1986-10-14 | — | — | US | disclosed |
| US-4535086-A | RODENTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0116277-A2 | Ketones of bicyclic compounds, process for their preparation, odorant and/or flavouring compositions containing such compounds | L. GIVAUDAN & CIE Société Anonyme (CH) | 1984-08-22 | — | — | EP | disclosed |
| EP-0098591-A1 | Heterocyclic compounds and rodenticides containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003784-A1 | Opsin-binding ligands, compositions and methods of use | CRYAB, CRYAA, UACA | NPSR1 2835/4885L3MBTL1 1042/4885MAPT 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.