Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014735 | 0.91 | BACE1 (0.54) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL6712976 | 0.91 | BACE1 (0.54) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL6715971 | 0.88 | PPARG (0.63) | MMP8ALDH1A1GAAPPARGRAB9A | |
| SCHEMBL27880853 | 0.87 | ATM (0.60) | ALDH1A1PSMB5POLBGAARAB9A | |
| SCHEMBL21428974 | 0.87 | CTSG (0.52) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL15343891 | 0.84 | MMP8 (0.59) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL27464748 | 0.84 | MMP8 (0.59) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL8966036 | 0.84 | MMP8 (0.59) | ELANEMMP8TP53ALDH1A1TACR1 | |
| SCHEMBL27481741 | 0.84 | GAA (0.50) | MMP8TP53ALDH1A1GAARAB9A | |
| SCHEMBL4765072 | 0.84 | MMP8 (0.59) | ELANEMMP8TP53ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210023034-A1 | PHENYLALANINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2021-01-28 | — | — | US | disclosed |
| WO-2019185907-A1 | PHENYLALANINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCERS | UNIVERSITE PARIS EST CRETEIL VAL DE MARNE (FR) | 2019-10-03 | — | — | WO | disclosed |
| EP-0528172-A1 | (2-Alkyl-3-pyridyl)methylpiperazine derivatives as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1993-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210023034-A1 | PHENYLALANINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCERS | IL4I1, PAH, IL4 | ELANE 3230/4885MMP8 3937/4885TP53 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.