SCHEMBL9575419

SCHEMBL9575419

CCOC(COCOCC(COC(C)C)OCC)COC(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25459932 0.88 LMNA (0.45) LMNATHRB
SCHEMBL9575740 0.83 HSD17B10 (0.35)
SCHEMBL9575515 0.82 LMNA (0.31) LMNA
SCHEMBL9575377 0.81
SCHEMBL9575759 0.79 PRKD3 (0.32)
SCHEMBL6988663 0.75
SCHEMBL208312 0.75 THRB (0.42) LMNATHRB
SCHEMBL14848965 0.74 THRB (0.33) LMNATHRB
SCHEMBL25612635 0.74 THRB (0.33) LMNATHRB
SCHEMBL5764246 0.74 LMNA (0.38) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225550-A PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
EP-0464511-A2 Process for the preparation of acyclic, substituted nucleosides and its intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-08 EP disclosed