Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575428 | 0.83 | HSD17B10 (0.45) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL9575419 | 0.83 | LMNA (0.36) | — | |
| SCHEMBL9575377 | 0.78 | — | — | |
| SCHEMBL9575549 | 0.78 | LPAR1 (0.40) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL209403 | 0.77 | HSD17B10 (0.50) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL18510371 | 0.76 | LPAR1 (0.58) | LPAR1LPAR3LPAR2DNM1 | |
| SCHEMBL9575759 | 0.76 | PRKD3 (0.32) | LPAR1LPAR3LPAR2 | |
| SCHEMBL12410368 | 0.75 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616848 | 0.75 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616857 | 0.75 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |