Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711032 | 0.86 | ALDH1A1 (0.34) | STAT3 | |
| SCHEMBL5264643 | 0.82 | CA1 (0.30) | — | |
| SCHEMBL10708684 | 0.75 | THRB (0.33) | STAT3 | |
| SCHEMBL9576755 | 0.72 | GAA (0.33) | — | |
| SCHEMBL9575374 | 0.72 | CA1 (0.38) | — | |
| SCHEMBL12636021 | 0.69 | — | — | |
| Methyl Alcohol SCHEMBL2775838 | 0.68 | TRPV4 (0.36) | — | |
| SCHEMBL9575667 | 0.68 | PDK1 (0.35) | — | |
| SCHEMBL9575647 | 0.68 | MEN1 (0.43) | — | |
| SCHEMBL10721123 | 0.68 | HSD17B10 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0249867-A2 | Substituted phenyl esters of alpha-fluoroacrylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-23 | — | — | EP | disclosed |