Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913776 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAPPIAPOLB | |
| SCHEMBL1821914 | 0.82 | MAPT (0.68) | MAPTHDAC8ALDH1A1SMN1; SMN2GAA | |
| Thiosalicylic Acid SCHEMBL1325384 | 0.81 | MAPT (0.70) | MAPTHDAC8ALDH1A1LMNAPOLB | |
| SCHEMBL9575558 | 0.79 | GSTA1 (0.49) | MAPTALDH1A1LMNAPPIAPOLB | |
| SCHEMBL9797365 | 0.79 | LIG1 (0.41) | MAPTALDH1A1LMNAPPIAPOLB | |
| SCHEMBL7636142 | 0.78 | TSHR (0.55) | ALDH1A1POLBTSHR | |
| SCHEMBL1200740 | 0.77 | AKR1C3 (0.55) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL9404648 | 0.76 | CA1 (0.44) | MAPTALDH1A1LMNAPPIAPOLB | |
| SCHEMBL31000747 | 0.76 | PPIA (0.45) | MAPTALDH1A1LMNAPPIAPOLB | |
| SCHEMBL6276445 | 0.76 | PPIA (0.45) | MAPTALDH1A1LMNAPPIAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0367671-A2 | Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | FOURNIER INDUSTRIE ET SANTE (FR) | 1990-05-09 | — | — | EP | disclosed |