Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821209 | 0.82 | ADRB2 (0.45) | TAS1R3TAS1R1HPGDMEN1POLB | |
| SCHEMBL3950960 | 0.79 | TAS1R3 (0.57) | THRATHRBTAS1R3TAS1R1HSD17B3 | |
| SCHEMBL13952520 | 0.77 | THRA (0.59) | THRATHRBHSD17B3MEN1LMNA | |
| SCHEMBL11603736 | 0.74 | TDP1 (0.59) | THRATHRBHPGDMEN1LMNA | |
| SCHEMBL6330127 | 0.74 | TDP1 (0.45) | HPGDLMNATDP1SMN1; SMN2NPC1 | |
| SCHEMBL634176 | 0.73 | HSD17B3 (0.55) | HSD17B3HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9417149 | 0.72 | ALDH1A1 (0.41) | THRATHRBHSD17B3HPGDLMNA | |
| SCHEMBL9347220 | 0.71 | CA1 (0.40) | THRBHPGDMEN1LMNAKMT2A | |
| SCHEMBL2239062 | 0.70 | HSP90AA1 (0.58) | THRATHRBHSD17B3HPGDMEN1 | |
| SCHEMBL9575803 | 0.69 | HSD17B3 (0.42) | THRATHRBHSD17B3HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | claimed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | claimed |
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5227291-A | METHOD FOR DETERMINATION OF ACID PHOSPHATASE ACTIVITY USING 4-ACYL-2, 6-DIHALOPHENYL PHOSPHORIC ACID DERIVATIVES | NITTO BOSEKI CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |