SCHEMBL9575818

SCHEMBL9575818

CCCCCCCCCCCCCCCCCCOC[C@H](COC(=O)NCCCl)OC(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 0.46
PLA2G2C Q5R387 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575848 0.90 LPAR6 (0.48) ACHE
SCHEMBL9575694 0.89 EPHX1 (0.46) ACHE
SCHEMBL9575816 0.83 LPAR5 (0.49) ACHE
Hydrochloric Acid SCHEMBL9576042 0.80 GMNN (0.43)
Hydrochloric Acid SCHEMBL9576039 0.80 GMNN (0.43)
SCHEMBL29250462 0.78 ACHE (0.73) ACHE
SCHEMBL9576035 0.78 TLR2 (0.49)
SCHEMBL24435889 0.78 LPAR1 (0.54) ACHE
SCHEMBL25005592 0.78 LPAR1 (0.54) ACHE
SCHEMBL10819280 0.78 ACHE (0.55) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5187293-A Blood platelet activating factor inhibitors HOFFMANN-LA ROCHE INC. (US) 1993-02-16 US disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed