Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 13/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863630 | 0.88 | ACHE (0.50) | LPAR5ACHEUSP2HTTCYP1A2 | |
| SCHEMBL9575848 | 0.85 | LPAR6 (0.48) | LPAR5ACHE | |
| SCHEMBL9863804 | 0.84 | LPAR5 (0.47) | LPAR5ACHEUSP2HTTCYP1A2 | |
| SCHEMBL9575818 | 0.83 | ACHE (0.46) | ACHE | |
| Hydrochloric Acid SCHEMBL9863876 | 0.83 | LPAR5 (0.46) | LPAR5ACHEUSP2HTT | |
| SCHEMBL9575694 | 0.82 | EPHX1 (0.46) | ACHE | |
| SCHEMBL29250462 | 0.81 | ACHE (0.73) | ACHEFAAH | |
| SCHEMBL16623920 | 0.79 | EPHX1 (0.59) | ACHE | |
| SCHEMBL4665172 | 0.78 | ACHE (0.49) | ACHEUSP2 | |
| SCHEMBL9575941 | 0.78 | KDM4E (0.57) | LPAR5USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |