Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR6 | P43657 | 3/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.48 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575818 | 0.90 | ACHE (0.46) | ACHE | |
| SCHEMBL9575694 | 0.86 | EPHX1 (0.46) | ACHE | |
| SCHEMBL9575816 | 0.85 | LPAR5 (0.49) | LPAR5ACHE | |
| SCHEMBL29250462 | 0.80 | ACHE (0.73) | ACHE | |
| SCHEMBL9576035 | 0.80 | TLR2 (0.49) | — | |
| SCHEMBL24470493 | 0.80 | LPAR1 (0.54) | LPAR1LPAR2LPAR3ACHE | |
| SCHEMBL10299549 | 0.80 | LPAR1 (0.54) | LPAR1LPAR2LPAR3ACHE | |
| SCHEMBL25005592 | 0.80 | LPAR1 (0.54) | LPAR1LPAR2LPAR3ACHE | |
| SCHEMBL10819280 | 0.80 | ACHE (0.55) | LPAR1LPAR2LPAR3ACHE | |
| SCHEMBL17431977 | 0.80 | ACHE (0.59) | LPAR1LPAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |