Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576265 | 1.00 | ALOX5 (0.45) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL3797454 | 0.84 | KMT2A (0.60) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9576131 | 0.82 | PTGS1 (0.50) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL9576141 | 0.82 | PTGS1 (0.50) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL15084628 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL28319570 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL28070065 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18734638 | 0.73 | RAB9A (0.50) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1128796 | 0.73 | CES2 (0.59) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10952556 | 0.71 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334119-B1 | COMPOUNDS FOR INHIBITING THE BIOSYNTHESIS OF LIPOXYGENASE-DERIVED METABOLITES OF ARACHIDONIC ACID | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| EP-0334119-A1 | Compounds for inhibiting the biosynthesis of lipoxygenase-derived metabolites of arachidonic acid | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1989-09-27 | — | — | EP | disclosed |