Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916526 | 0.87 | MAPT (0.97) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL9577236 | 0.86 | MAPT (0.62) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL15915230 | 0.85 | MAPT (1.00) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL4000366 | 0.85 | ALDH1A1 (0.70) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL15915182 | 0.78 | MAPT (0.87) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL20509604 | 0.76 | MAPT (0.62) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL8355318 | 0.75 | LMNA (0.60) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL7888147 | 0.75 | GAA (0.65) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL11228520 | 0.74 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 | |
| SCHEMBL128275 | 0.74 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1LMNAMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |