Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577115 | 0.86 | MAPT (0.74) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL15916526 | 0.79 | MAPT (0.97) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL4000366 | 0.77 | ALDH1A1 (0.70) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL15915230 | 0.77 | MAPT (1.00) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL9577211 | 0.75 | MAPT (0.44) | MAPTHTTMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5504038 | 0.74 | ALDH1A1 (0.61) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL10082160 | 0.71 | MAPK1 (1.00) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2834532 | 0.71 | MAPK1 (1.00) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL13846055 | 0.71 | MAPK1 (1.00) | MAPTHTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL12719599 | 0.71 | MAPK1 (1.00) | MAPTHTTMAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |