Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784566 | 0.83 | CA1 (0.56) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL1291097 | 0.83 | CA1 (0.56) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL1460042 | 0.82 | LMNA (0.46) | ALDH1A1TSHRCYP1A2EDNRAEDNRB | |
| SCHEMBL31371128 | 0.82 | ALDH1A1 (0.44) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL9577227 | 0.82 | LMNA (0.40) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL7360565 | 0.81 | NSD2 (0.51) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL6740814 | 0.80 | CA2 (0.47) | CA1CA2CA4CA6EDNRA | |
| SCHEMBL9577180 | 0.79 | RECQL (0.50) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL31371051 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL10453957 | 0.77 | RECQL (0.59) | ALDH1A1CA1CA2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |