Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577165 | 0.85 | ALDH1A1 (0.54) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL9577236 | 0.75 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL9577107 | 0.74 | ALDH1A1 (0.54) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL9780478 | 0.73 | MAPK1 (0.57) | USP2CA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15915716 | 0.71 | CA1 (0.60) | MAPTUSP2CA1CA2MEN1 | |
| SCHEMBL15915670 | 0.71 | CA1 (0.60) | MAPTUSP2CA1CA2MEN1 | |
| SCHEMBL9577208 | 0.70 | PTGES2 (0.41) | CA1CA2MEN1KMT2A | |
| SCHEMBL9577237 | 0.69 | KEAP1 (0.50) | CA1CA2MEN1KMT2AALDH1A1 | |
| SCHEMBL9577227 | 0.68 | LMNA (0.40) | MAPTCA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9577212 | 0.66 | HTT (0.50) | CA1CA2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4959500-A | Polybrominated bis sulfonamides | ETHYL CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |