Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308170 | 0.82 | ALOX5 (0.52) | ALOX5F2 | |
| SCHEMBL9577510 | 0.74 | ALOX5 (0.60) | ALOX5F2 | |
| SCHEMBL9577523 | 0.72 | ALOX5 (0.58) | ALOX5F2 | |
| SCHEMBL11348436 | 0.71 | SLC6A3 (0.50) | SLC6A3 | |
| SCHEMBL22717056 | 0.70 | KMT2A (0.54) | ALOX5 | |
| SCHEMBL9598079 | 0.70 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL25890731 | 0.69 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9151512 | 0.69 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9150430 | 0.69 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL10656521 | 0.69 | ALOX5 (0.69) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214069-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |
| US-5132328-A | Lipoxygenase inhibitors as antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-21 | — | — | US | disclosed |