Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577507 | 0.82 | ALOX5 (0.50) | ALOX5F2 | |
| SCHEMBL25890731 | 0.82 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL22717056 | 0.79 | KMT2A (0.54) | ALOX5 | |
| SCHEMBL9309092 | 0.78 | MAPT (0.38) | — | |
| SCHEMBL9577510 | 0.78 | ALOX5 (0.60) | ALOX5F2 | |
| SCHEMBL9308093 | 0.76 | MRGPRX4 (0.51) | ALOX5F2 | |
| SCHEMBL9577523 | 0.76 | ALOX5 (0.58) | ALOX5F2 | |
| SCHEMBL9308680 | 0.74 | ALOX5 (0.52) | ALOX5PRKDC | |
| SCHEMBL10656521 | 0.73 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL9150430 | 0.73 | ALOX5 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |