Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355334 | 0.79 | PMP22 (0.32) | KCNN4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15355335 | 0.79 | PMP22 (0.32) | KCNN4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15355336 | 0.79 | PMP22 (0.32) | KCNN4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL957774 | 0.78 | GAA (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL957713 | 0.77 | HDAC6 (0.33) | KCNN4HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL957710 | 0.77 | HDAC6 (0.33) | KCNN4HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL116411 | 0.76 | OPRM1 (0.34) | HDAC6ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL957772 | 0.73 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL15368372 | 0.73 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL3647417 | 0.69 | KCNN4 (0.38) | KCNN4KCNE1KCNQ1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015157-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | Vitae Pharmaceuticals ,Inc. | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015157-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | HSD11B1, HSD11B2, HSD3B1 | KCNN4 3172/4885KCNE1 3110/4885KCNQ1 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.