Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CTH | P32929 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467542 | 0.77 | LDHA (0.40) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL11384778 | 0.76 | MGAM (0.42) | TSHRKDM4E | |
| SCHEMBL1304727 | 0.75 | LDHA (0.38) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL269347 | 0.74 | TDP1 (0.33) | TSHRFFAR3TDP1 | |
| SCHEMBL4879417 | 0.73 | TDP1 (0.38) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL954279 | 0.73 | LDHA (0.47) | LDHASRRHMGCRCHRM1TBXA2R | |
| SCHEMBL85014 | 0.73 | TSHR (0.42) | HMGCRCHRM1TBXA2RADRA1APOLB | |
| SCHEMBL21907862 | 0.72 | GLRA1 (0.32) | KDM4E | |
| SCHEMBL10892961 | 0.72 | TSHR (0.32) | POLBTSHR | |
| SCHEMBL14715593 | 0.70 | LDHA (0.44) | LDHASRRHMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376859-B1 | METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | claimed |