Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505385 | 0.85 | MAPT (0.36) | MAPTTSHRHPGDCYP2C19ALOX12 | |
| SCHEMBL10409103 | 0.69 | — | — | |
| SCHEMBL1726442 | 0.69 | — | — | |
| SCHEMBL1971717 | 0.67 | TSHR (0.37) | MAPTTSHRHPGDCYP2C19ALOX12 | |
| SCHEMBL5435647 | 0.66 | PTGS2 (0.37) | ALDH1A1 | |
| SCHEMBL3891715 | 0.64 | POLB (0.32) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL550589 | 0.64 | PAX8 (0.32) | MAPTHPGD | |
| SCHEMBL7631134 | 0.64 | ALDH1A1 (0.38) | TSHRAKT1ALDH1A1 | |
| SCHEMBL30130340 | 0.63 | CA4 (0.33) | — | |
| SCHEMBL1617969 | 0.63 | MAPT (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236997-A | Curable fluorosilicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |