Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685002 | 0.70 | GLRA3 (0.46) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL19677848 | 0.67 | CA2 (0.54) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL3950 | 0.67 | SMN1; SMN2 (1.00) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.67 | SMN1; SMN2 (1.00) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL4170581 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL20660368 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11857289 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL11859223 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL7075597 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL9343307 | 0.65 | SMN1; SMN2 (0.95) | CA2SMN1; SMN2ALDH1A1POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | claimed |
| JP-5194393-A | — | — | None | — | — | JP | disclosed |
| JP-H05194393-A | 2,6-DIMETHYL-4-(4'-HYDROXY-3',5'-DI-TERT.-BUTYLPHENYL)-1,4-DIHYDROPYRIDINE DERIVATIVE, ITS PRODUCTION AND USE AS FREE RADICAL SCAVENGER | INST DE INVESTIGACION Y DESARROLLO QUIMICO BIOLOGICO SA | 1993-08-03 | — | — | JP | disclosed |
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |