Diphenylether

Diphenylether

SCHEMBL9580832

CCCC[Si](OC)(OC)OC.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.56
TSHR P16473 1/20 0.44
MAPT P10636 3/20 0.44
HTT P42858 2/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CA4 P22748 1/20 0.41
HDAC3 O15379 1/20 0.41
LMNA P02545 1/20 0.41
ALOX12 P18054 1/20 0.40
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
POLB P06746 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL9580898 0.89 LTA4H (0.54) LTA4HTSHRMAPTHTTALDH1A1
SCHEMBL19816665 0.85 LTA4H (0.43) LTA4HTSHRMAPTHTTALDH1A1
SCHEMBL1608986 0.85 LTA4H (0.43) LTA4HTSHRMAPTHTTALDH1A1
Benzene SCHEMBL27743707 0.84 LMNA (0.52) LTA4HTSHRLMNA
Aniline SCHEMBL2117721 0.81 TSHR (0.41) LTA4HTSHRMAPTALDH1A1LMNA
Diphenylether SCHEMBL9580840 0.80 LTA4H (0.52) LTA4HTSHRHTTCA4LMNA
SCHEMBL5396830 0.80 LMNA (0.40) LTA4HTSHRMAPTHTTALDH1A1
SCHEMBL19816823 0.80 LTA4H (0.43) LTA4HMAPTHTTALDH1A1GAA
SCHEMBL19816471 0.80 LTA4H (0.39) LTA4HTSHRMAPTHTTALDH1A1
Diphenylether SCHEMBL9334093 0.80 LTA4H (0.76) LTA4HTSHRMAPTHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523242-A1 CURABLE RESIN COMPOSITION KANSAI PAINT CO. LTD. (JP) 1993-01-20 EP disclosed