Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28522885 | 0.69 | METAP1 (0.50) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL8534761 | 0.68 | ALDH1A1 (0.52) | ALDH1A1GAAHSD17B10MAPTHPGD | |
| SCHEMBL11533101 | 0.67 | KMT2A (0.40) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL6381696 | 0.66 | FOLH1 (0.50) | ALDH1A1HSD17B10KMT2AMEN1HPGD | |
| SCHEMBL10614240 | 0.66 | ALDH1A1 (0.42) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL23128214 | 0.66 | ALDH1A1 (0.44) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL17211829 | 0.66 | CYP24A1 (0.44) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL8792164 | 0.66 | TSHR (0.34) | KAT2BALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL14062161 | 0.65 | CYP26A1 (0.55) | BRD4 | |
| SCHEMBL8792741 | 0.65 | TSHR (0.38) | ALDH1A1GAAHSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235059-A | Topically treating ocular hypertension and glaucoma | MERCK & CO., INC. (US) | 1993-08-10 | — | — | US | disclosed |