Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | DRD1 | P21728 | 6/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | DRD5 | P21918 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581908 | 0.93 | TDP1 (0.56) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL9582681 | 0.92 | HTR7 (0.53) | HTR7 | |
| SCHEMBL9582259 | 0.92 | KMT2A (0.54) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL9581488 | 0.90 | DRD4 (0.49) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL9582106 | 0.90 | KDM4E (0.48) | KDM4EALOX15APEX1KMT2AHSD17B10 | |
| SCHEMBL10646279 | 0.87 | MAOB (0.45) | DRD2HTR1ADRD1DRD4DRD5 | |
| SCHEMBL9582658 | 0.85 | HTR7 (0.61) | HTR7 | |
| SCHEMBL11357559 | 0.85 | DRD2 (0.54) | KMT2ATDP1DRD2HTR1ADRD4 | |
| SCHEMBL9581369 | 0.84 | HTR7 (0.57) | HTR7 | |
| SCHEMBL9581356 | 0.84 | KDM4E (0.64) | KDM4EALOX15APEX1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256673-A | Indole-3-yl-A-tetrahydropyridyl or piperidyl compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-10-26 | — | — | US | disclosed |