Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581542 | 1.00 | ALDH1A1 (0.36) | ALDH1A1IDO1DRD3HPGDCNR1 | |
| SCHEMBL9582131 | 1.00 | ALDH1A1 (0.36) | ALDH1A1IDO1DRD3HPGDCNR1 | |
| SCHEMBL9299207 | 0.86 | CYP1A2 (0.37) | IDO1ABCB1CNR2 | |
| SCHEMBL7768331 | 0.86 | CYP1A2 (0.37) | IDO1ABCB1CNR2 | |
| SCHEMBL7874514 | 0.85 | IDO1 (0.33) | IDO1ABCB1CNR2 | |
| SCHEMBL15257382 | 0.79 | ALDH1A1 (0.36) | ALDH1A1DRD3HPGDCNR1CYP19A1 | |
| SCHEMBL5868357 | 0.79 | IDO1 (0.40) | ALDH1A1IDO1ABCB1MAPT | |
| SCHEMBL6274078 | 0.79 | IDO1 (0.40) | ALDH1A1IDO1ABCB1MAPT | |
| SCHEMBL5868353 | 0.79 | IDO1 (0.40) | ALDH1A1IDO1ABCB1MAPT | |
| SCHEMBL8947014 | 0.78 | IDO1 (0.36) | IDO1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | disclosed |