Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27170735 | 0.88 | KDM4E (0.45) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL6671333 | 0.86 | ALDH1A1 (0.47) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL958236 | 0.83 | EGFR (0.48) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL29607317 | 0.83 | EGFR (0.48) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17847407 | 0.82 | PTGDR2 (0.57) | ALDH1A1SMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL17847396 | 0.80 | TRPV4 (0.43) | MAPK1CYP2C19PTGDR2HTTLMNA | |
| SCHEMBL986849 | 0.79 | KDM4E (0.49) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL4856058 | 0.78 | KDM4E (0.47) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL10651246 | 0.77 | KDM4E (0.42) | ALDH1A1NPSR1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL7456145 | 0.75 | THRA (0.54) | NPSR1SMN1; SMN2MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |
| CN-101675060-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, their preparation and use | SANOFI AVENTIS | 2010-03-17 | — | — | CN | disclosed |
| EP-1440117-A2 | POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | Ciba SC Holding AG (CH) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003031507-A2 | POLYESTER AND POLYAMIDE COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-17 | — | — | WO | disclosed |
| US-20010009939-A1 | STABILIZERS FOR POWDER COATINGS | CIBA SPECIALTY CHEMICALS CORP. | 2001-07-26 | — | — | US | disclosed |