Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.53 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215322 | 0.90 | ACHE (1.00) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL29120936 | 0.80 | ALDH1A1 (1.00) | ACHEALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL30632945 | 0.80 | ALDH1A1 (1.00) | ACHEALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL19407335 | 0.76 | CYP1A2 (0.66) | ACHEALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL9734944 | 0.75 | ACHE (0.69) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL9735885 | 0.74 | ACHE (0.62) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL9583756 | 0.74 | ACHE (0.56) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL9165590 | 0.73 | ACHE (0.53) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL9583258 | 0.73 | ACHE (0.59) | ACHEALDH1A1CYP1A2BCHEHSD17B10 | |
| SCHEMBL9167709 | 0.71 | ACHE (0.62) | ACHEALDH1A1CYP1A2BCHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202440-A | Certain 9-amino-2-(or 4)-oxa 1,2,3,4-tetrahydro- or 1,2,3,4,5,6,7,8-octahydro-acridines | PFIZER INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0311303-A2 | 4-aminopyridine derivatives | PFIZER INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1989002739-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| WO-1989002740-A1 | 4-AMINOPYRIDINE DERIVATIVES | PFIZER INC. (US) | 1989-04-06 | — | — | WO | disclosed |