Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531012 | 0.79 | SLC6A3 (0.43) | SLC6A3SLC6A4CYP3A4ALDH1A1LMNA | |
| SCHEMBL8531014 | 0.79 | SLC6A3 (0.43) | SLC6A3SLC6A4CYP3A4ALDH1A1LMNA | |
| SCHEMBL9587145 | 0.78 | ALDH1A1 (0.50) | SLC6A3SLC6A4CYP3A4MEN1NPC1 | |
| SCHEMBL8533007 | 0.74 | ALDH1A1 (0.43) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8534980 | 0.74 | ALDH1A1 (0.43) | SLC6A3SLC6A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8535755 | 0.72 | CYP3A4 (0.47) | SLC6A3SLC6A4CYP3A4MEN1NPC1 | |
| SCHEMBL8532285 | 0.72 | CYP3A4 (0.47) | SLC6A3SLC6A4CYP3A4MEN1NPC1 | |
| SCHEMBL3519183 | 0.71 | SLC6A3 (0.55) | SLC6A3SLC6A4CYP3A4MEN1NPC1 | |
| SCHEMBL3604519 | 0.68 | SLC6A3 (0.56) | SLC6A3SLC6A4CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL13073555 | 0.68 | SLC6A3 (0.54) | SLC6A3SLC6A4CYP3A4POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248834-A | Pesticides | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-09-28 | — | — | US | disclosed |
| EP-0179788-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4777185-A | Phenyl phenoxyphenyl propenyl cyclopropane pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-10-11 | — | — | US | disclosed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | disclosed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | disclosed |