Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531014 | 1.00 | SLC6A3 (0.43) | SLC6A3SLC6A4CYP3A4CYP2D6LMNA | |
| SCHEMBL8535755 | 0.81 | CYP3A4 (0.47) | SLC6A3SLC6A4CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL8532285 | 0.81 | CYP3A4 (0.47) | SLC6A3SLC6A4CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL9585481 | 0.79 | SLC6A3 (0.44) | SLC6A3SLC6A4CYP3A4LMNACYP1A2 | |
| SCHEMBL8531125 | 0.76 | FAAH (0.41) | ALDH1A1 | |
| SCHEMBL8531130 | 0.76 | FAAH (0.41) | ALDH1A1 | |
| SCHEMBL8534980 | 0.75 | ALDH1A1 (0.43) | SLC6A3SLC6A4LMNAALDH1A1 | |
| SCHEMBL8533007 | 0.75 | ALDH1A1 (0.43) | SLC6A3SLC6A4LMNAALDH1A1 | |
| SCHEMBL8530639 | 0.73 | SLC6A3 (0.36) | SLC6A3SLC6A4CYP3A4CYP2C19 | |
| SCHEMBL8530637 | 0.73 | SLC6A3 (0.36) | SLC6A3SLC6A4CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |