Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533007 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4ESLC6A4SLC6A3MEN1 | |
| SCHEMBL8533005 | 0.80 | — | — | |
| SCHEMBL8535755 | 0.78 | CYP3A4 (0.47) | KDM4ESLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8532285 | 0.78 | CYP3A4 (0.47) | KDM4ESLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8529945 | 0.77 | HSD11B1 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8529941 | 0.77 | HSD11B1 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8531171 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8531175 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8531014 | 0.75 | SLC6A3 (0.43) | ALDH1A1SLC6A4SLC6A3LMNA | |
| SCHEMBL8531012 | 0.75 | SLC6A3 (0.43) | ALDH1A1SLC6A4SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |