Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585086 | 0.84 | ACHE (0.39) | PKMTP53TSHRALDH1A1KMT2A | |
| SCHEMBL9711718 | 0.83 | PKM (0.49) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9585783 | 0.82 | PKM (0.53) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9585718 | 0.80 | PKM (0.56) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9840312 | 0.79 | PKM (0.57) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9711860 | 0.78 | PKM (0.51) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9711779 | 0.78 | PKM (0.42) | PKMMAPTALDH1A1PPARGTDP1 | |
| SCHEMBL9711931 | 0.78 | PKM (0.42) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL9585797 | 0.78 | PKM (0.56) | PKMMAPTTP53TSHRALDH1A1 | |
| SCHEMBL6099389 | 0.75 | PKM (0.76) | PKMMAPTTP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212316-A | Respiratory system disorders | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-05-18 | — | — | US | disclosed |
| EP-0303227-B1 | ETHERS AND THIOETHERS HAVING THERAPEUTICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-02-05 | — | — | EP | disclosed |
| US-4968706-A | MUCOLYTIC, ANTITUSSIVE, BRONCHODILATOR, ANTIINFLAMMATORY | BOEHRINGER MANNHEIN ITALIA, S.P.A. (IT) | 1990-11-06 | — | — | US | disclosed |