Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736614 | 0.85 | MME (0.39) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL9587952 | 0.84 | MME (0.47) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL6735727 | 0.83 | MME (0.40) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL8837468 | 0.82 | CTRB1 (0.57) | MMENPSR1L3MBTL1CA12CA1 | |
| SCHEMBL7435120 | 0.80 | MME (0.43) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL8837469 | 0.79 | FCER2 (0.50) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL7450894 | 0.79 | MME (0.52) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL9068533 | 0.78 | MME (0.62) | MMECYP3A4MAPK1PAM | |
| SCHEMBL9587602 | 0.78 | MME (0.48) | MMECYP3A4MAPK1CYP1A2CYP2D6 | |
| SCHEMBL6731374 | 0.78 | MME (0.48) | MMEFCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |