Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588686 | 0.88 | CA1 (0.48) | CA1CA2CA5ACA9TDP1 | |
| SCHEMBL10502876 | 0.84 | CA1 (0.44) | CA1CA2CA5ACA9TDP1 | |
| SCHEMBL6054812 | 0.83 | CA1 (0.50) | CA1CA2CA5ACA9TDP1 | |
| SCHEMBL9743094 | 0.77 | CA1 (0.47) | CA1CA2CA5ACA9SMN1; SMN2 | |
| SCHEMBL9587373 | 0.75 | CA1 (0.48) | CA1CA2CA5ACA9TDP1 | |
| SCHEMBL4286897 | 0.73 | F2 (0.43) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL10865204 | 0.72 | ALDH1A1 (0.41) | TDP1L3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9586448 | 0.70 | CA1 (0.40) | CA1CA2CA5ACA9SMN1; SMN2 | |
| SCHEMBL9584994 | 0.70 | CA1 (0.34) | CA1CA2CA5ACA9SMN1; SMN2 | |
| SCHEMBL8848745 | 0.69 | CA1 (0.46) | CA1CA2CA5ACA9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5213608-A | Sulfonylguanidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| US-5167692-A | Pre- and postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-01 | — | — | US | disclosed |
| EP-0431270-A1 | Substituted sulfonylamidinohydrazones | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |