Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404819 | 0.91 | ALOX15 (0.60) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404814 | 0.85 | ALOX15 (0.63) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9405000 | 0.85 | ALOX15 (0.62) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404950 | 0.85 | ADRB2 (0.75) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404934 | 0.83 | ALOX15 (0.59) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404837 | 0.82 | ALOX15 (0.64) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404924 | 0.81 | ADRB2 (0.58) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL2816724 | 0.81 | ALOX15 (0.61) | ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL9404947 | 0.81 | ALOX15 (0.63) | ALOX15ADRB2DRD1ADRA2ADRD2 | |
| SCHEMBL9404786 | 0.80 | ALOX15 (0.68) | ALOX15ADRB2DRD1ADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246949-A | And lactic acid esters, treatment of hypotension and cardiac circulatory insufficiency | SANSHO CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |