Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586883 | 1.00 | RAB9A (0.39) | RAB9AMAOBROCK1PRKACACDC7 | |
| SCHEMBL9586885 | 1.00 | RAB9A (0.39) | RAB9AMAOBROCK1PRKACACDC7 | |
| SCHEMBL9588478 | 0.77 | GPR52 (0.43) | RAB9AMAOBHPGDPLOD2PLOD3 | |
| SCHEMBL9588484 | 0.77 | GPR52 (0.43) | RAB9AMAOBHPGDPLOD2PLOD3 | |
| SCHEMBL9588485 | 0.77 | GPR52 (0.43) | RAB9AMAOBHPGDPLOD2PLOD3 | |
| SCHEMBL28250552 | 0.76 | AKR1C3 (0.44) | MAOBRPS6KA3TAAR1HPGDALDH1A1 | |
| SCHEMBL14604992 | 0.71 | TAAR1 (0.39) | MAOBTAAR1ALDH1A1LMNA | |
| SCHEMBL18899058 | 0.71 | NAMPT (0.43) | ROCK1PRKACACDC7PLK4CHEK1 | |
| SCHEMBL20708210 | 0.70 | L3MBTL1 (0.39) | HPGDPLOD2PLOD3ALDH1A1CYP1A2 | |
| SCHEMBL3282677 | 0.69 | ALDH1A1 (0.53) | RAB9AROCK1PRKACACDC7PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |